2 supplements compared

Best Supplements for Migraine Prevention

Adults with episodic migraine seeking evidence-based prevention, those on standard preventives wanting adjunctive support, and adults whose neurologist has discussed CoQ10

Written by Editorial Team·Medically reviewed by Angelique Nicole R. Villegas, RND

Supplement Comparisons

Which Supplement Is Best for Migraine Prevention?

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CoQ10

Moderate Evidence

CoQ10 has Level B evidence for migraine prevention from the American Headache Society. Compare the best CoQ10 products, backed by the Sandor 2005 RCT.

4 products rankedHeart health & energy

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Magnesium

Limited Evidence

Magnesium reduced migraine frequency 41.6% vs 15.8% placebo in an RCT. Learn which forms work best and why oxide is a weaker choice.

4 products rankedSleep, stress & muscle health

This content is for educational purposes only and is not medical advice. These statements have not been evaluated by the FDA. Always consult your healthcare provider before starting any supplement.